Application of indocyanine green fluorescence visualization in surgical resection of abdominal wall endometriosis
10.3760/cma.j.cn112141-20210919-00533
- VernacularTitle:吲哚菁绿荧光显影应用于腹壁子宫内膜异位症切除术中的初步探讨
- Author:
Yanchun LIANG
1
;
Dan LIAO
;
Yajing WEI
;
Jiaming HUANG
;
Tingting WU
;
Ruyu YANG
;
Biqi HUANG
;
Xing WANG
;
Shuzhong YAO
Author Information
1. 中山大学附属第一医院妇科，广州 510080
- Keywords:
Abdominal wall;
Endometriosis;
Indocyanine green;
Optical imaging;
Laparoscopy;
Gynecologic surgical procedures
- From:
Chinese Journal of Obstetrics and Gynecology
2021;56(12):849-855
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the feasibility, effectiveness and safety of indocyanine green (ICG) navigation in the surgical resection of abdominal wall endometriosis (AWE).Methods:Seven women undergoing surgery for AWE in First Affiliated Hospital of Sun Yat-sen University (from July 1, 2021 to October 1, 2021) were collected. After exposure of the focus, ICG were used intravenously (0.25 mg/kg) as fluorescent dye for the intraoperative evaluation of AWE vascularization. Resection of the AWE was guided by direct visualization of the focus under standard laparoscopy with a near-infrared (NIR) camera head. Surgical margin around the AWE (3, 6, 9 and 12 point) and the margin under the focus were obtained for postoperative pathological examination of endometriosis. Time from injection to fluorescence visualization, the proportion of fluorescence visualization, time of fully resection of AWE, side effects related to the use of ICG, perioperative complications as well as the pathological result of the surgical margins were recorded.Results:ICG fluorescence of the AWE were seen in 5 patients (5/7). The mean time from injection to fluorescence visualization was (46.7±9.8) s. The mean time of fully resection of AWE was (16.4±7.0) minutes. There were no side effects related to the use of ICG. The rate of class-A wound healing was 7/7. All of the surgical margins were confirmed endometriosis-negative by postoperative pathological examination.Conclusion:ICG fluorescence visualization could conduct accurate resection of AWE, which is clinically safe and effective.
