The study on brain biometry and cerebral hemodynamics in fetuses with hypoplastic left heart syndrome in the second trimester of gestation
10.3760/cma.j.cn131148-20210325-00196
- VernacularTitle:中孕期左心发育不良综合征胎儿脑生物学指标和脑血流动力学研究
- Author:
Menghua CHEN
1
;
Ye ZHANG
;
Xiaoyan GU
;
Lin SUN
;
Xiaowei LIU
;
Ying ZHAO
;
Jiancheng HAN
;
Xuehao GONG
;
Yihua HE
Author Information
1. 深圳大学第一附属医院 深圳市第二人民医院超声科 518035
- Keywords:
Ultrasonography;
Hypoplastic left heart syndrome;
Head circumference;
Middle cerebral artery;
Cerebrovascular hemodynamics
- From:
Chinese Journal of Ultrasonography
2021;30(9):772-777
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the changes of biparietal diameter, head circumference and cerebrovascular hemodynamics in fetuses with hypoplastic left heart syndrome (HLHS) during middle pregnancy.Methods:The biparietal diameter, head circumference, middle cerebral artery pulsatility index (MCA-PI), umbilical artery pulsatility index (UA-PI) and MCA-PI/UA-PI (CPR) of 41 fetuses with HLHS(HLHS group) were retrospectively analyzed from January 2015 to December 2019 in Beijing Anzhen Hospital, and were compared with those of 82 normal fetuses matched for gestational age at the same period (control group).Results:The Z-scores of head circumference, MCA-PI and CPR in with HLHS group were lower than in control group(all P<0.05); Head circumference in HLHS group were weakly and positively correlated with the MCA-PI and CPR ( r=0.385, 0.416; all P<0.05). Conclusions:There are some changes in the head circumference and cerebral hemodynamics in fetuses with HLHS during mid-gestational age, and the head circumference is weakly and positively correlated with MCA-PI and CPR, which has clinical significance.
