Research progress in exosomes in repair of spinal cord injury

VernacularTitle:外泌体对脊髓损伤修复作用的研究进展
Author: Jian CHEN ¹ ; Shujie ZHAO ; Mengyuan WU ; Zheng ZHOU ; Xiaowei WANG ; Jin FAN ; Guoyong YIN
Author Information

1. 南京医科大学第一附属医院（江苏省人民医院）骨科　210029
Keywords: Spinal cord injuries; Exosomes; Signal transduction
From: Chinese Journal of Trauma 2021;37(1):85-92
CountryChina
Language:Chinese
Abstract: Spinal cord injury is a common clinical disease secondary to spinal cord fractures that causes patients with motor and sensory dysfunction or even paralysis. In recent years, exosomes have participated in the occurrence and development of various diseases as nanometer-sized cell particles, and have received extensive attention. Exosomes derived from spinal cord tissue cells during spinal cord injury affect the injury process and tissue repair. In addition, exosomes as a new treatment for spinal cord injury have been widely studied. The authors document the mechanisms of various exosomes from spinal cord tissue and the repair effects of various cell-derived exosomes in spinal cord injury, in order to deepen the understanding of the role of exosomes in spinal cord injury and provide new ideas for studying the course and treatment of spinal cord injury.