Epidemiological characteristics and etiological study of hand-feet-mouth disease in Dali Bai Autonomous Prefecture from 2015 to 2019
10.3760/cma.j.cn311365-20210311-00089
- VernacularTitle:2015年至2019年大理白族自治州手足口病的流行病学和病原学构成分析
- Author:
Yanjun LIU
1
;
Feiyun DUAN
;
Zuo HE
;
Fang GUAN
Author Information
1. 大理白族自治州疾病预防控制中心，云南省 671000
- Keywords:
Hand, foot and mouth disease;
Epidemiological characteristics;
Etiology
- From:
Chinese Journal of Infectious Diseases
2021;39(11):676-680
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the epidemiological and etiological characteristics of hand-feet-mouth disease (HFMD) in Dali Bai Autonomous Prefecture and to provide scientific evidence for the prevention of HFMD.Methods:The HFMD cases during January 2015 to December 2019 in Dali Bai Autonomous Prefecture were collected through the Chinese Information System for Disease Control and Prevention. The demographic data, incidence rate of HFMD and epidemiological characteristics were analysed. Coxsackie virus A16(CoxA16), enterovirus 71(EV71) and other enterovirus nucleic acid in stool samples of HFMD patients were detected by real-time reverse transcription polymerase chain reaction. Chi-square test was used as statistical method.Results:From 2015 to 2019, 30 730 cases of HFMD were reported in Dali Bai Autonomous Prefecture. The annual incidence rate was 171.50/100 000, and the incidence rate was on rise from 2016 to 2019. There were 24(0.08%) severe cases. Yongping County, Binchuan County and Dali City were with the top three average annual incidence rate. The peak incidence was from June to July in summer, 9 168 cases (29.83%) were reported. The peak incidence was from September to October in autumn, 5 988 cases (19.49%) were reported. The epidemic intensity in summer was higher than that in autumn. Among 30 730 cases, there were 17 373 males and 13 357 females. The annual incidence rate of male patients was 120.29/100 000, and that of female was 75.83/100 000. The difference was statistically significant ( χ2=1 637.467, P<0.01). The highest incidence was in infancy (one to
