Analysis on the relationship between pulmonary tuberculosis and vitamin D in Qinghai Province
10.3760/cma.j.cn311365-20201109-00841
- VernacularTitle:青海省肺结核与维生素D关系的分析
- Author:
Yongxue LI
1
;
Zhaofen WANG
;
Yuqing WANG
;
Xueping CAO
;
Xiaoping YAN
;
Bin LI
;
Xiaodong SU
;
Quanlu ZHANG
;
Yue SHANG
;
Ling WANG
Author Information
1. 青海大学医学院公共卫生系，西宁 810001
- Keywords:
Tuberculosis, pulmonary;
Mycobacterium tuberculosis;
Vitamin D
- From:
Chinese Journal of Infectious Diseases
2021;39(9):524-527
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the vitamin D level of pulmonary tuberculosis patients in Qinghai Province, and to explore the correlation between vitamin D level and pulmonary tuberculosis.Methods:From May to September 2020, 208 bacterial confirmed pulmonary tuberculosis patients who were admitted to The 4th People′s Hospital of Qinghai Province were enrolled as the pulmonary tuberculosis group, and 129 healthy people who underwent physical examination during the same period were enrolled as the healthy control group. Independent sample t test and chi-square test were used for statistical analysis. Results:The deficiency rate of vitamin D was 11.06%(23/208) in the pulmonary tuberculosis group, which was higher than that (3.10%(4/129)) in the healthy control group, and the difference was statistically significant ( χ2=6.840, P=0.009). The vitamin D level was (56.84±20.03) μg/L in the pulmonary tuberculosis group, which was lower than that ((67.39±17.07) μg/L) in the healthy control group, and the difference was statistically significant ( t=5.154, P<0.01). The vitamin D levels were not different between the newly treated ((56.66±20.02) μg/L)) and retreated pulmonary tuberculosis patients ((59.11±20.81) μg/L) ( t=0.468, P=0.650). The vitamin D level of simple pulmonary tuberculosis patients ((57.82±20.01) μg/L) was higher than that of pulmonary tuberculosis patients combined with other diseases ((48.08±18.46) μg/L), and the difference was statistically significant ( t=2.132, P=0.034). Conclusion:Pulmonary tuberculosis is associated with decreased vitamin D levels, and patients with pulmonary tuberculosis are more likely to suffer from decreased or deficient vitamin D, which suggests clinicians considering the vitamin D status when treating pulmonary tuberculosis patients.
