Research progress of neuroregeneration and multimodal neuromodulation in the treatment of spinal cord injury
10.3760/cma.j.cn101721-20210322-00020
- VernacularTitle:神经再生、多模态神经调制治疗脊髓损伤的研究进展
- Author:
Haoming FENG
1
;
Shanzi YU
;
Xiaobo ZHANG
;
Wanjiang FENG
;
Jianlong WANG
Author Information
1. 中南大学湘雅三医院脊柱外科，长沙 410000
- Keywords:
Spinal cord injury;
Neuroregeneration;
Multimodal neuromodulation;
Decompression surgery;
Hormone therapy;
Therapeutic hypothermia
- From:
Clinical Medicine of China
2021;37(5):474-479
- CountryChina
- Language:Chinese
-
Abstract:
Spinal cord injury has a high rate of disability in clinical practice, which can be divided into complete SCI and incomplete SCI according to different injury segments and severity.The main purpose of treatment is to protect the nerves.At present, acute spinal cord injury is mainly treated with surgical decompression, neurotrophic treatment, hormone therapy, hypothermia therapy, rehabilitation intervention and other clinical comprehensive treatment.In recent years, breakthroughs have been made in the field of endogenous and exogenous neural stem cell research, and important progress has been made in the basic research of stem cell transplantation.In the long run, nerve regeneration and nerve modulation may be the most promising therapy for the repair of spinal cord injury.
