Short term efficacy of early postoperative intestinal microecological therapy for gastric cancer
10.3760/cma.j.cn431274-20210708-00737
- VernacularTitle:胃癌术后早期肠道微生态治疗的短期疗效观察
- Author:
Fang WU
1
;
Hongmei YANG
;
Wenfa LIN
;
Zaiyuan YE
;
Songyang WU
;
Zhiyuan BO
;
Zhenguang CHEN
;
Yao LUO
Author Information
1. 树兰（杭州）医院胃肠外科 310000
- Keywords:
Stomach neoplasms;
Intestinal microecology;
Enteral nutrition
- From:
Journal of Chinese Physician
2021;23(7):974-977
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the short-term effect of early application of intestinal microecological therapy after gastric cancer surgery.Methods:A retrospective analysis was made on 96 patients with early and middle stage gastric cancer who underwent surgical treatment in the department of gastrointestinal surgery of Shulan (Hangzhou) Hospital from June 1, 2020 to May 31, 2021. Among them, 48 patients in the observation group were given enteral nutrition support treatment in the early stage after operation and intestinal microecological preparation, while the control group of 48 patients in the early postoperative were given enteral nutrition support. The serum total protein, albumin, prealbumin and other nutrition related indexes and immune related indexes such as CD4 + , CD8 + , CD4 + /CD8 + were detected before and 7 days after operation. The clinical indexes such as the time of first anal exhaust and the incidence of infectious complications were recorded. Results:There was no significant difference between the two groups in preoperative serum total protein, albumin, prealbumin and immune related indexes such as CD4 + , CD8 + , CD4 + /CD8 + ( P>0.05). 7 days after operation, the above indexes in the observation group were significantly higher than those in the control group (all P<0.05). The anal exhaust recovery time of observation group was faster ( P<0.05); There was no significant difference in the incidence of postoperative infectious complications between the two groups ( P>0.05). Conclusions:Early application of intestinal microecological agents in patients with gastric cancer after operation can significantly improve the nutritional status and immune function, promote the recovery of intestinal function, and will not increase the incidence of complications.
