A Multicenter Retrospective Case Study of Anaphylaxis Triggers by Age in Korean Children.
- Author:
So Yeon LEE
1
;
Kangmo AHN
;
Jihyun KIM
;
Gwang Cheon JANG
;
Taek Ki MIN
;
Hyeon Jong YANG
;
Bok Yang PYUN
;
Ji Won KWON
;
Myung Hyun SOHN
;
Kyung Won KIM
;
Kyu Earn KIM
;
Jinho YU
;
Soo Jong HONG
;
Jung Hyun KWON
;
Sung Won KIM
;
Tae Won SONG
;
Woo Kyung KIM
;
Hyung Young KIM
;
You Hoon JEON
;
Yong Ju LEE
;
Hae Ran LEE
;
Hye Young KIM
;
Youngmin AHN
;
Hye Yung YUM
;
Dong In SUH
;
Hyun Hee KIM
;
Jin Tack KIM
;
Jeong Hee KIM
;
Yong Mean PARK
;
Sooyoung LEE
Author Information
- Publication Type:Multicenter Study ; Original Article
- Keywords: Anaphylaxis; children; epidemiology
- MeSH: Anaphylaxis*; Anti-Bacterial Agents; Arachis; Child*; Contrast Media; Egg White; Epidemiology; Fagopyrum; Humans; Juglans; Korea; Male; Medical Records; Milk; Retrospective Studies*; Seafood; Tertiary Care Centers; Triticum
- From:Allergy, Asthma & Immunology Research 2016;8(6):535-540
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: Although anaphylaxis is recognized as an important, life-threatening condition, data are limited regarding its triggers in different age groups. We aimed to identify anaphylaxis triggers by age in Korean children. METHODS: We performed a retrospective review of medical records for children diagnosed with anaphylaxis between 2009 and 2013 in 23 secondary or tertiary hospitals in South Korea. RESULTS: A total of 991 cases (mean age=5.89±5.24) were reported, with 63.9% involving patients younger than 6 years of age and 66% involving male children. Food was the most common anaphylaxis trigger (74.7%), followed by drugs and radiocontrast media (10.7%), idiopathic factors (9.2%), and exercise (3.6%). The most common food allergen was milk (28.4%), followed by egg white (13.6%), walnut (8.0%), wheat (7.2%), buckwheat (6.5%), and peanut (6.2%). Milk and seafood were the most common anaphylaxis triggers in young and older children, respectively. Drug-triggered anaphylaxis was observed more frequently with increasing age, with antibiotics (34.9%) and nonsteroidal anti-inflammatory drugs (17.9%) being the most common causes. CONCLUSIONS: The most common anaphylaxis trigger in Korean children was food. Data on these triggers show that their relative frequency may vary by age.
