Correlation between enlarged perivascular spaces and the imaging markers of cerebrovascular disease in patients with ischemic stroke
10.3760/cma.j.cn371468-20210126-00057
- VernacularTitle:缺血性卒中患者血管周围间隙扩大与脑小血管病影像学标志物的相关性
- Author:
Xuejiao QIN
1
;
Zhenjie TENG
;
Qiang SUN
;
Peiyuan LYU
;
Yanhong DONG
Author Information
1. 华北理工大学研究生学院，唐山 063210
- Keywords:
Ischemic stroke;
Enlarged perivascular spaces;
Cerebrovascular disease;
Imaging markers
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2021;30(8):701-707
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the correlation between enlarged perivascular spaces and other imaging markers of cerebrovascular disease in patients with ischemic stroke.Methods:Totally 287 patients with ischemic stroke hospitalized in neurology department from January 2018 to January 2019 were selected. According to the severity of EPVS in different parts of the brain, the correlations between the severity of EPVS in different parts of the brain and cerebral microbleeds (CMBs), white matter hyperintensity (WMH), lacunar infarcts (LIs) were analyzed. SPSS 22.0 software was used for analysis. Chi-square test, independent sample t-test, rank-sum test and non parametric Mann-Whitney U test were used for group comparison, and Logistic regression analysis was used for multivariate analysis. Results:EPVS was common and severe in patients with ischemic stroke. Periventricular white matter hyperintensity(PWMH)( β=1.604, P<0.001, OR=4.971, 95% CI=2.015-12.263), CMBs ( β=1.224, P=0.018, OR=3.339, 95% CI=1.232-9.383) and LIs ( β=0.626, P=0.047, OR=1.871, 95% CI=1.009-3.470) were independent risk factors for BG-EPVS. PWMH ( r=0.614), DWMH ( r=0.622), LIs ( r=0.532) were positively correlated with the severity of BG-EPVS (all P<0.01). Conclusion:The imaging makers of CSVD are related to BG-EPVS, which can affect the severity of brain BG-EPVS in patients with ischemic stroke.
