Effects of repetitive transcranial magnetic stimulation on sleep quality in patients with sleep disorder after stroke: systematic review and meta-analysis
10.3760/cma.j.issn.1008-6706.2021.12.010
- VernacularTitle:重复经颅磁刺激对脑卒中后睡眠障碍患者睡眠质量的系统评价与Meta分析
- Author:
Liyan YANG
1
;
Jinghui LAI
;
Yangfan CAI
;
Jing WENG
;
Ling LIN
;
Ting RAO
;
Kunshan LIN
;
Renxiong ZHANG
Author Information
1. 福建中医药大学附属康复医院睡眠医学科,福州 350003
- Keywords:
Transcranial magnetic stimulation;
Physical therapy modalities;
Stroke;
Sleep initiation and maintenance disorders;
Meta-analysis;
Case-control studies;
Tre
- From:
Chinese Journal of Primary Medicine and Pharmacy
2021;28(12):1803-1808
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) on sleep quality in patients with post-stroke sleep disorder (PSSD).Methods:The clinical randomized controlled trials involving PSSD patients who received rTMS were retrieved from nine medical databases. After excluding duplicated references, screening for independent references and risk evaluation, the remaining references were input into RevMan5.4 software for meta-analysis.Results:Twelve eligible literatures were included in the final analysis. Meta-analysis results revealed that after rTMS intervention, there were significant differences in the following terms between the treatment and control groups (all P < 0.05): Pittsburgh sleep quality index score [MD = -2.60, 95% CI (-3.03, -2.17), P < 0.000 01]; sleep latency [MD = -9.69, 95% CI (- 16.87, - 2.50), P < 0.01], sleep efficiency [MD = 8.90, 95% CI (5.41, 12.39), P < 0.01], number of awakenings [MD = -1.15, 95% CI (- 2.26, - 0.04), P = 0.04], awakening duration [MD = -10.95, 95% CI (- 13.30, -8.61), P < 0.01], and rapid eye movement [MD = 4.54, 95% CI (2.24, 6.85), P < 0.01] in polysomnography; brain-derived neurotrophic factor score [MD = 5.29, 95% CI (2.47, 8.11), P = 0.0002]; clinical curative rate [ OR = 4.46, 95% CI (2.75, 7.23), P < 0.000 01]. Conclusion:rTMS can improve the sleep quality in patients with PSSD, which is worthy of clinical promotion.
