Efficacy of Xiatianwu eye drops combined with raceanisodamine eye drops in the treatment of pseudomyopia in children
10.3760/cma.j.issn.1008-6706.2021.08.023
- VernacularTitle:夏天无滴眼液联合消旋山莨菪碱滴眼液治疗儿童假性近视的疗效观察
- Author:
Lingling LIU
1
;
Lijun JIANG
;
Yongwei ZHU
Author Information
1. 浙江省，嘉兴市中医医院眼科 313100
- Keywords:
Myopia;
Diopter;
Intraocular pressure;
Adverse reactions;
Xiaxiawu eye drops;
Raceanisodamine eye drops;
Child
- From:
Chinese Journal of Primary Medicine and Pharmacy
2021;28(8):1228-1232
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the efficacy and safety of Xiatianwu eye drops in the treatment of pseudomyopia in children. Methods:A total of 8 000 children with pseudomyopia who received treatment in Jiaxing Hospital of Traditional Chinese Medicine between June 2018 and June 2019 were included in this study. They were randomly assigned to receive treatment with either raceanisodamine eye drops (control group, n = 4 000) or Xiatianwu eye drops combined with raceanisodamine eye drops (observation group, n = 4 000) for 30 successive days (1 treatment course). The uncorrected visual acuity and diopter in each group were detected by an 'E' chart and optometry. Axial eye length and intraocular pressure in each group were measured using an ophthalmic A/B ultrasound scanner and a non-contact tonometer to assess the therapeutic effects. The incidence of adverse reactions during the treatment period was calculated. Results:After 30 days of treatment, the uncorrected visual acuity in the observation group was significantly higher than that in the control group [(0.88 ± 0.33) vs. (0.81 ± 0.29), t = 10.077, P < 0.001]. The diopter in the observation group was significantly lower than that in the control group [(-0.99 ± 0.36) D vs. (-1.07 ± 0.39) D, t = 9.533, P < 0.001]. Total effective rate in the observation group was significantly higher than that in the control group (91.10% vs. 88.18%, χ2 = 18.422, P < 0.001). There were no significant differences in the axial eye length, intraocular pressure and the incidence of adverse reactions between the two groups (all P > 0.05). Conclusion:Xiatianwu eye drops combined with raceanisodamine eye drops in the treatment of pseudomyopia in children can improve uncorrected visual acuity, increase therapeutic effects, and does not increase the incidence of adverse reactions.
