Importance of Accurate Diagnosis in Pyoderma Gangrenosum.
10.7181/acfs.2014.15.3.138
- Author:
Yoon Soo KIM
1
;
Han Kyeol KIM
;
Yea Sik HAN
Author Information
1. Department of Plastic and Reconstructive Surgery, Kosin University College of Medicine, Busan, Korea. hanplastic1@naver.com
- Publication Type:Case Report
- Keywords:
Pyoderma gangrenosum;
Necrotizing fasciitis;
Malignant neoplasms
- MeSH:
Cyclosporine;
Diagnosis*;
Diagnosis, Differential;
Fasciitis, Necrotizing;
Humans;
Immunosuppressive Agents;
Necrosis;
Pyoderma Gangrenosum*;
Skin Diseases;
Steroids;
Ulcer
- From:Archives of Craniofacial Surgery
2014;15(3):138-141
- CountryRepublic of Korea
- Language:English
-
Abstract:
Pyoderma gangrenosum is a rare inflammatory reactive dermatosis marked by painful cutaneous ulcers. Diagnosis of pyoderma gangrenosum is usually made based on past medical history and after the exclusion of other possible diseases based on the clinical manifestations of the lesion. Diseases that show rapid progression to necrosis and that should not be misdiagnosed as pyoderma gangrenosum include malignant neoplasms and necrotizing fasciitis. Immunosuppressive agents such as steroids and cyclosporine are considered first-line therapy. Surgical removal of the necrotic tissues is contraindicated, as it may further induce immune reaction and promote ulcer to enlarge. Here, we present a case to encourage plastic surgeons to consider pyodermagangrenosum in the differential diagnosis of idiopathic ulcers. Satisfactory outcomes for patients with pyodermagangrenosum may be expected when using steroids and immunosuppressive agents during the early stage of the disease.
