Ultrasonographic features of cervical lymph node metastasis and their relationship with the expression of cell proliferation-associated nuclear antigen
10.3760/cma.j.issn.1008-6706.2021.06.008
- VernacularTitle:颈部淋巴结转移癌超声影像特点及其与细胞核增殖相关抗原表达的关系
- Author:
Meijin GUO
1
;
Xiangping YAO
;
Huali CHEN
Author Information
1. 浙江衢化医院超声科,衢州 324004
- Keywords:
Neoplasm metastasis;
Lymphatic metastasis;
Ultrasonography;
Echolocation;
Regional blood flow;
Proliferating cell nuclear antigen
- From:
Chinese Journal of Primary Medicine and Pharmacy
2021;28(6):835-838
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the ultrasonographic features of cervical lymph node metastasis and analyze their relationship with the expression of cell proliferation-associated nuclear antigen (Ki-67).Methods:The clinical data of 92 patients with cervical lymph node metastasis who received treatment in Zhejiang Quhua Hospital, China between June 2017 and July 2019 were retrospectively analyzed. The correlation between ultrasonographic features of cervical lymph node metastasis and Ki-67 expression was analyzed.Results:Among the 92 patients, 158 metastatic lymph nodes were confirmed by pathological examination. The main ultrasonic imaging features were the length ratio of long diameter to short diameter < 2 in 119 (75.32%) lymph nodes, disappearance of portal hyperechoic signal in 127 (80.38%) lymph nodes, punctate hyperechoic signal in 108 (68.35%) lymph nodes, cystic degeneration in 57 (36.08%) lymph nodes, mixed types of peripheral blood flow signal in 124 (78.48%) lymph nodes, microcalcification in 123 (77.85%) lymph nodes. The length ratio of long diameter to short diameter < 2, punctate hyperechoic signal and mixed types of peripheral blood flow signal were correlated with high expression of Ki-67 ( χ2 = 24.252, 15.732, 17.033, all P < 0.05). Conclusion:High expression of Ki-67 is correlated with the length ratio of long diameter to short diameter < 2, punctate hyperechoic signal and mixed types of peripheral blood flow signal in cervical lymph node metastasis.
