Clinical analysis of 82 cases of brucellosis with first symptom of joint pain
10.3760/cma.j.cn231583-20200312-00036
- VernacularTitle:以关节痛为首发症状的82例布鲁菌病患者的临床分析
- Author:
Xiaojuan NIU
1
;
Xiaohong LUO
;
Fengxia HAN
;
Xuan WANG
;
Jun DU
;
Jin XU
;
Chunyu WANG
Author Information
1. 中国人民解放军联勤保障部队第九四医院风湿免疫科，甘肃兰州 730050
- Keywords:
Brucellosis;
Joint pain;
Clinical manifestations
- From:
Chinese Journal of Endemiology
2021;40(7):593-595
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the characteristics and diagnosis and treatment of brucellosis with joint pain as the first clinical manifestation, and summarize the clinical classification of brucellosis complicated with joint pain, so as to provide reference for clinical diagnosis and treatment.Methods:Cases of brucellosis with first symptom of joint pain diagnosed in the 940th Hospital of PLA Joint Logistic Support Force from January 2015 to January 2020 were selected. The main clinical features, laboratory examination, diagnosis and treatment were analyzed.Results:A total of 82 patients with joint pain of the first symptom were selected, including 61 males and 21 females. Joint pain was the main complaint of the patients, 63.4% (52/82) of the patients visited spine surgery department, 17.1% (14/82) visited minimally invasive orthopedics department, 12.2% (10/82) visited rheumatic immunology department, and 7.3% (6/82) visited traditional Chinese medicine department. Brucellosis patients with cervical lesions accounted for 22.0% (18/82), combined with lumbar lesions accounted for 51.2% (42/82). The patients with elevated C-reactive protein accounted for 68.3% (56/82), abnormal liver function accounted for 52.4% (43/82), anti "O" positive accounted for 3.7% (3/82), abnormal autoantibodies accounted for 6.1% (5/82), and human leukocyte antigen-B27 (HLA-B27) positive accounted for 12.2% (10/82). Four patients with HLA-B27 positive had sacroiliac arthritis. All patients were cured after standard and full course therapy.Conclusion:Joint pain may be the first symptom of brucellosis, and the lumbar spine and cervical spine are the most vulnerable parts.
