A Case of Extraocular Sebaceous Carcinoma Arising from Nevus Sebaceus.
- Author:
Jae Hui NAM
1
;
Young Jun CHOI
;
Tae Hwan KIM
;
Ga Young LEE
;
Won Serk KIM
;
Kea Jeung KIM
Author Information
1. Department of Dermatology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. gygy.lee@samsung.com
- Publication Type:Case Report
- Keywords:
Nevus sebaceus;
Scalp;
Sebaceous carcinoma
- MeSH:
Adult;
Biopsy;
Eyelids;
Female;
Humans;
Immunohistochemistry;
Mucin-1;
Nevus;
Scalp;
Sebaceous Glands
- From:Korean Journal of Dermatology
2009;47(3):326-329
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sebaceous carcinoma (SC) is a slow-growing, locally aggressive tumor with the high potency of metastatic spread. This neoplasm frequently arises from the sebaceous glands of the eyelid and exceptionally from extraocular sites. Approximately one-quarter of all reported cases of SC are extraocular. We observed a 42-year-old woman with an crusted erythematous to brownish plaque on her scalp. The biopsy specimen showed that multiple lobules were composed of foamy-cytoplasmic cells and sebocytes which show pleomorphism and atypia. For the immunohistochemistry, abundant tumor cells (with the expressions of epithelial membrane antigens and cytokeratin) were found within the masses. We present here a case of SC of the scalp arising from a previous lesion clinically compatible with a nevus sebaceous.
