Risk factors of hypotension after ligation of patent ductus arteriosus in very/extremely low birth weight infants
10.3760/cma.j.issn.2096-2932.2021.06.005
- VernacularTitle:极低/超低出生体重儿动脉导管未闭结扎术后低血压的危险因素分析
- Author:
Xuehui ZHENG
1
;
Fang YAO
;
Chun CHEN
;
Yanliang YU
;
Bingchun LIN
;
Jie ZHAO
;
Zhifeng HUANG
;
Chuanzhong YANG
Author Information
1. 南方医科大学附属深圳妇幼保健院新生儿科 518028
- Keywords:
Infant, very low birth weight;
Infant, extremely low birth weight;
Patent ductus arteriosus;
Hypotension;
Risk factors
- From:Chinese Journal of Neonatology
2021;36(6):23-27
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the risk factors of hypotension after ligation of patent ductus arteriosus (PDA) in very/extremely low birth weight infants (VLBWI/ELBWI).Method:From March 2016 to January 2021, preterm infants with birth weight <1 500 g receiving bedside PDA ligation in the neonatal intensive care unit (NICU) of our hospital were enrolled in the study. According to the occurrence of hypotension within 72 hours after ligation, the infants were assigned into non-hypotension group and hypotension group. The general status and perioperative conditions of the two groups were analyzed. Multivariate Logistic regression was used to analyze the risk factors of hypotension.Result:A total of 44 cases were enrolled, including 33 in non-hypotension group and 11 in hypotension group. Univariate analysis showed that hypotension group had significantly more cases with body weight <1 100 g during surgery and receiving preoperative high frequency oscillatory ventilation (HFOV) than non-hypotension group ( P<0.05). Multivariate Logistic regression analysis showed that weight <1 100 g during surgery ( OR=12.045, 95% CI 1.351~107.394, P=0.026) and receiving preoperative HFOV ( OR=27.832, 95% CI 1.363~568.292, P=0.031)were independent risk factors of hypotension. Conclusion:Hypotension is one of the common complications of PDA ligation in VLBWI/ELBWI. The infant's body weight during ligation and receiving preoperative HFOV are independent risk factors of hypotension.
