Management and prognosis of infantile hepatic hemangioendothelioma-arteriovenous fistula complicated with heart failure in neonates
10.3760/cma.j.issn.2096-2932.2021.04.004
- VernacularTitle:新生儿肝脏血管内皮细胞瘤-动静脉瘘合并心力衰竭的诊治及结局
- Author:
Juan DU
1
;
Fei JIN
;
Hailan WU
;
Jie YIN
;
Xu ZHENG
;
Ying LIU
;
Jingwen WENG
;
Yujie QI
;
Mingyan HEI
Author Information
1. 国家儿童医学中心，首都医科大学附属北京儿童医院新生儿中心 100045
- Keywords:
Infant,newborn;
Infantile hepatic hemangioendothelioma;
Arteriovenous fistula;
Congestive heart failure;
Interventional therapy
- From:Chinese Journal of Neonatology
2021;36(4):17-21
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the clinical features and prognosis of infantile hepatic hemangioendothelioma-arteriovenous fistula (IHHE-AVF) complicated with heart failure in neonates.Method:From May 2016 to June 2020, neonates with IHHE-AVF complicated with heart failure admitted were retrospectively studied. The clinical presentation, treatment and outcomes were analyzed.Result:A total of 11 cases of IHHE-AVF complicated with heart failure were enrolled (male 5, female 6). The onset age of heart failure was 12.0 (0.0, 17.0) d. 6 cases showed IHHE on fetal ultrasound. All patients had significantly enlarged heart on chest X-ray. All patients had decreased left ventricular systolic function and pulmonary hypertension on echocardiography. All patients required respiratory support and 6 of them were intubated. 3 cases received conservative treatment (all dead). 1 case received surgery (dead). 7 cases received interventional therapy at the age of (25.6±18.5) d. 1 case was dead, and the other 6 cases were improved and discharged. All the 6 cases were followed up to 3~18 months. None of them had heart failure again. The IHHE were shrunk or completely disappeared. Coagulation function and platelet count were normal.Conclusion:The fatality rate of neonatal-onset IHHE-AVF complicated with heart failure is extremely high. Interventional therapy may be more effective than conservative therapy and surgery.
