Research progress on prognosis factors of in-hospital cardiac arrest in children
10.3760/cma.j.issn.1673-4912.2021.11.015
- VernacularTitle:儿童院内心脏骤停预后相关因素的研究进展
- Author:
Xufeng LI
1
;
Yuxiong GUO
Author Information
1. 广东省心血管病研究所,广东省人民医院(广东省医学科学院)儿科重症监护室,广州 510080
- Keywords:
Cardiac arrest;
Prognosis;
In-hospital;
Cardiopulmonary resuscitation;
Children
- From:
Chinese Pediatric Emergency Medicine
2021;28(11):1005-1009
- CountryChina
- Language:Chinese
-
Abstract:
Thousands of children experience cardiac arrest in hospital each year, and only about half of them can survive to hospital discharge.Recognizing cardiac arrest in time and initiating high-quality cardiopulmonary resuscitation as early as possible is the key to improve the prognosis.During resuscitation, the longer the duration of cardiopulmonary resuscitation, the lower the survival rate.To prevent the heart rhythm from deteriorating into ventricular fibrillation, pulseless ventricular tachycardia and other malignant rhythms, timely use of adrenaline is beneficial to improve survival.For shockable heart rhythms, the recommended initial dose of defibrillation is 2 J/kg.Invasive airways can be harmful during resuscitation.For qualified medical institutions, choosing appropriate cases to perform extracorporeal cardiopulmonary resuscitation as soon as possible will improve the prognosis.After resuscitation, normal oxygen supply and normal pressure ventilation should be maintained, and physiological monitoring such as arterial diastolic pressure and end-tidal carbon dioxide should be used to guide post-resuscitation management.However, mild hypothermia treatment does not bring benefits to improve the prognosis.Imaging tests such as EEG, CT, and magnetic resonance imaging can assess the prognosis of nerves after resuscitation early, while neuron-specific enolase, S100 calcium binding protein, and somatosensory evoked potential have better predictive value, but lacking of enough clinical data.