Clinical characteristics and risk factors for plastic bronchitis caused by severe mycoplasma pneumonia in children
10.3760/cma.j.issn.1673-4912.2021.08.007
- VernacularTitle:儿童重症肺炎支原体肺炎所致塑型性支气管炎的临床特点及危险因素分析
- Author:
Huisheng YAO
1
;
Liyun LIU
;
Lili YI
;
Lina HAN
;
Qianlan ZHOU
;
Miao LI
;
Xiaohua HAN
Author Information
1. 中国医科大学附属盛京医院小儿呼吸内科，沈阳 110004
- Keywords:
Severe mycoplasma pneumoniae pneumonia;
Plastic bronchitis;
Children;
Fiberoptic bronchoscopy
- From:
Chinese Pediatric Emergency Medicine
2021;28(8):673-678
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize the clinical characteristics of plastic bronchitis caused by severe mycoplasma pneumoniae pneumonia in children, to find the risk factors for plastic bronchitis, and to provide references for judging the prognosis and comprehensively formulating treatment plans.Methods:We retrospectively analyzed the clinical data(146 cases)of children with severe mycoplasma pneumoniae pneumonia who underwent bronchoscopy in the Department of Pediatric Respiratory Medicine of Shengjing Hospital of China Medical University from January 2017 to December 2019.According to whether it was plastic bronchitis, all patients were divided into plastic bronchitis group(68 cases) and non-plastic bronchitis group(78 cases), and the gender, age, laboratory examination indicators, imaging characteristics and treatment of children were collected under the circumstances.The single factor with clinical significance and statistical significance would be subjected to multivariate Logistic regression analysis.Results:There were no significant differences in gender, age, heat duration, white blood cell count, C-reactive protein value, and interleukin-6 value between the two groups(all P>0.05). The percentage of neutrophils, alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, D-dimer, number of cases of pleural effusion, length of hospital stay, and number of endoscopy in the plastic bronchitis group were higher than those in non-plastic bronchitis group, the number of right upper lobe consolidation cases was less than that in the non-plastic bronchitis group, and the differences were statistically significant( P<0.05). Multiple Logistic regression analysis showed that pleural effusion( OR=4.898, 95% CI 2.195-10.926) and lactate dehydrogenase ( OR=1.051, 95% CI 1.003-1.101) were independent predictors of plastic bronchitis in children with severe mycoplasma pneumoniae pneumonia. Conclusion:For children with severe mycoplasma pneumoniae pneumonia, if lung CT shows that the upper lobe of the non-right lung is uniformly compacted and complicated with pleural effusion, lactate dehydrogenase is significantly increased, and attention should be paid to the possibility of plastic bronchitis.Timely improvement of fiberoptic bronchoscopy may shorten the course of the disease and reduce the occurrence of complications.
