Henoch Schonlein purpura and antacids
10.3760/cma.j.issn.1673-4912.2021.06.018
- VernacularTitle:过敏性紫癜与抑酸剂
- Author:
Jing LI
1
;
Zhiqin MAO
Author Information
1. 中国医科大学附属盛京医院小儿消化科，沈阳 110004
- Keywords:
Henoch Schonlein purpura;
H 2-receptor antagonists;
Proton pump inhibitors;
Antacids
- From:
Chinese Pediatric Emergency Medicine
2021;28(6):529-531
- CountryChina
- Language:Chinese
-
Abstract:
Henoch Schonlein purpura(HSP), also known as immunoglobulin A vasculitis, is the most common vasculitis in children, which involves skin, gastrointestinal tract, joints and kidney.Glucocorticoid is the conventional treatment for HSP patients with digestive system symptoms.Antacids, including H 2-receptor antagonists and proton pump inhibitors, are often used in combination with glucocorticoids in order to avoid the adverse reactions of glucocorticoids therapy.Antacids may play a role in the treatment of HSP patients by alleviating gastrointestinal symptoms, adjuvant treatment of secondary acute pancreatitis, inhibiting Helicobacter pylori and reducing the adverse reactions of glucocorticoids.However, there are few studies and more exploration is needed.
