Therapeutic strategies of pediatric anti-N-methyl-D-aspartate receptor encephalitis
10.3760/cma.j.issn.1673-4912.2021.06.003
- VernacularTitle:儿童抗N-甲基-D-天门冬氨酸受体脑炎的治疗策略
- Author:
Jing PENG
1
;
Linxiu ZHONG
Author Information
1. 中南大学湘雅医院儿科,长沙 410008
- Keywords:
Anti-N-methyl-D-aspartate receptor encephalitis;
Immunotherapy;
Autoimmune encephalitis;
Children
- From:
Chinese Pediatric Emergency Medicine
2021;28(6):453-457
- CountryChina
- Language:Chinese
-
Abstract:
Anti-N-methyl-D-aspartate receptor(NMDAR)encephalitis is an autoimmune disorder mediated by anti-NMDAR antibody.It can be found in both adults and children.Anti-NMDAR encephalitis in children is different from adults in inducement, clinical manifestation, diagnosis process, treatment, follow-up strategy, and prognosis.Although the clinical manifestation of the disease is serious, timely and effective immunotherapy can make the vast majority of children get a good prognosis.Therefore, the review summarized and analyzed the treatment progress, in order to improve the standard diagnosis and treatment of pediatric anti-NMDAR encephalitis in China, and reduce the morbidity and mortality.