Correlation between capillary filling time and lactate clearance rate in patients with septic shock
10.3760/cma.j.cn211501-20210112-00121
- VernacularTitle:感染性休克患者不同部位毛细血管充盈时间与乳酸清除率的相关性研究
- Author:
Wenbo CUI
1
;
Zunzhu LI
;
Qi LI
;
Jianhua SUN
;
Hongbo LUO
;
Mingxi ZHAO
;
Haibo DENG
Author Information
1. 中国医学科学院 北京协和医院重症医学科 100730
- Keywords:
Septic shock;
Capillary refill time;
Lactate clearance
- From:
Chinese Journal of Practical Nursing
2021;37(19):1458-1461
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the correlation between capillary filling time (CRT) and lactate clearance rate in patients with septic shock, so as to provide reference for the clinical application of CRT in patients with septic shock.Methods:A prospective study was conducted on 70 patients with septic shock. CRT, mean arterial pressure (map) and sequential organ failure (SOFA) score, Acute Physiology and Chronic Health Evaluation Scoring System (APACHE Ⅱ) score, mechanical ventilation and lactate clearance rate were collected at 3 sites (forehead, knee and nail bed) respectively at 2 time points after admission and 6 hours after admission. The correlation between CRT changes and lactate clearance rate was compared.Results:When lactate clearance rate of more than 10% in 6 hours, the Pearson coefficients of the three sites were 0.823 for nail bed ( P<0.05), 0.232 for forehead and 0.254 for knee ( P>0.05). When lactate clearance rate of less than 10% in 6 hours, the Pearson coefficients of the three sites were 0.299 for nail bed, 0.247 for forehead and 0.254 for knee ( P>0.05). Conclusion:When lactate clearance rate of more than 10% in 6 hours, there is a good correlation between the CRT of nail bed and the lactate clearance rate of patients. The CRT of nail bed can be a practical tool for clinical evaluation of microcirculation.
