Observation of the theutic effect of dual-channel thrombolytic urokinase method on acute thrombosis of internal fistula
10.3760/cma.j.cn211501-20200609-02692
- VernacularTitle:双通道溶栓尿激酶法对内瘘急性血栓治疗效果的观察
- Author:
Yao LU
1
;
Siyi LI
;
Duozi WANG
;
Xiaoqing TAN
;
Xiaojun YANG
;
Xiao HE
Author Information
1. 南方医科大学深圳医院血液透析中心 518110
- Keywords:
Arteriovenous fistula;
Vascular access;
Double-channel urokinase thrombolysis method
- From:
Chinese Journal of Practical Nursing
2021;37(18):1377-1381
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the observation of the short-term recanalization rate and safety of acute thrombosis of arteriovenous fistula by dual-channel urokinase thrombolysis.Methods:A total of 52 dialysis patients with acute thrombosis of arteriovenous fistula in the Department of Nephrology, Shenzhen Hospital of Southern Medical University from January 2017 to January 2020 were selected. They were divided into control group and observation group by random number table. Twenty-seven cases in the test group used inflow arterial puncture and venous thrombosis, hereinafter referred to as dual channel, and bolus injection of urokinase for thrombolysis. Twenty-five cases in the control group were treated with tradi) ional peripheral intravenous bolus injection of urokinase for thrombolysis, and the recanalization time of internal fistula, adverse reactions and safety of thrombolysis were compared between the two groupsResults::The early (2 hours) reopening rate of the test group was 92.6% (25/27), which was higher than that of the control group by 44.0% (11/25) ( χ2 value was 14.389, P<0.05), which was statistically significant. The embolization site of the two groups of patients ( χ2 value was 2.989, P>0.05), the access situation of the two groups of patients ( χ2 value was 0.277, P>0.05), no statistical significance. There was no statistical significance in subcutaneous ecchymosis ( χ2 value was 0.088, P>0.05), bleeding at the puncture point ( χ2 value was 0.003, P>0.05), and puncture injury ( χ2 value was 0.944, P>0.05) in both groups. Conclusions:The double-channel urokinase thrombolysis method has the characteristics of high (2 hours) early recanalization rate, safe and effective in the treatment of acute arteriovenous fistula thrombosis.
