Research progress of Worster-Drought syndrome
10.3760/cma.j.cn101070-20201016-01624
- VernacularTitle:Worster-Drought综合征研究进展
- Author:
Ziwei HUANG
1
;
Bingtao HE
;
Yujun ZHAN
;
Jianguo CAO
Author Information
1. 中国医科大学深圳儿童医院康复科，广东 深圳 518038
- Keywords:
Worster-Drought syndrome;
Congenital pseudobulbar paralysis;
Cerebral palsy
- From:
Chinese Journal of Applied Clinical Pediatrics
2021;36(22):1754-1757
- CountryChina
- Language:Chinese
-
Abstract:
Worster-Drought syndrome (WDS) is a special and rare type of cerebral palsy, which is characte-rized by pseudobulbar palsy, selective weakness of the muscles of the lips, tongue, and soft palate, dysarthria, dysphagia, salivation, and jaw spasm.The onset of WDS is linked with a variety of prenatal, intrapartum and postnatal factors.The report of family cases of WDS suggested the genetic predisposition.Although there is no cure at present, early genetic counseling, early diagnosis and intervention can reduce the morbidity of offspring and improve the symptoms of children with WDS, which will greatly reduce the burden on the family and society in the future.In the present study, this paper aims to explore the etiology, pathogenesis, clinical manifestation, imaging examination, diagnosis, disease spectrum and current treatment of WDS, thus improving the diagnostic and therapeutic efficacy.
