Follow-up of nutrition support and treatment in an infant with severe malnutrition secondary to Tricho-hepato-enteric syndrome
10.3760/cma.j.cn101070-20200419-00676
- VernacularTitle:发-肝-肠综合征继发重度营养不良婴儿营养支持治疗及随访
- Author:
Guiping KONG
1
;
Zhifeng LIU
;
Bixia ZHENG
;
Yu JIN
;
Jian PAN
Author Information
1. 南京医科大学附属儿童医院消化科 210008
- Keywords:
Tricho-hepato-enteric syndrome;
Infant;
Malnutrition;
Nutrition support
- From:
Chinese Journal of Applied Clinical Pediatrics
2021;36(20):1579-1581
- CountryChina
- Language:Chinese
-
Abstract:
Clinical data, nutrition support and 6-year follow-up results of a patient with Tricho-hepato-enteric syndrome (THES) diagnosed in the Children′s Hospital of Nanjing Medical University in December 2013 were analyzed.The patient suffered severe malnutrition, growth retardation, hypophosphatemia, hypoglobulinemia, high nutritional risk status and significant intestinal dysfunction.The genetic testing revealed SKIV2 L gene variation in this case of THES.During the acute exacerbation of diarrhea, enteral nutrition and periodical short-term parenteral nutrition were given as nutrition support.Deep-hydrolyzed formula by oral and low-fat, low-residue, high-quality-protein diet was given during the remission phase.At last, the diarrhea and nutritional status of the patient improved gradually.The growth and development, including neuromotor development of the case also caught up to children with the same age, and he was capable of schooling.It is suggested that rational individualized nutrition support can significantly improve intestinal function and nutritional status of children with THES, which overcome the dangerous period, improve the quality of life and prolong the survival time.
