Case report of bacterial meningitis complicated with posterior fossa subdural empyema in a newborn
10.3760/cma.j.cn101070-20200331-00547
- VernacularTitle:新生儿细菌性脑膜炎并后颅窝硬膜下积脓1例
- Author:
Mei LI
1
;
Hua YANG
;
Qiuji TAO
;
Yawen XUE
;
Rong LUO
;
Qianyun CAI
Author Information
1. 四川大学华西第二医院儿科，四川大学出生缺陷与相关妇儿疾病教育部重点实验室，成都 610041
- Keywords:
Subdural empyema;
Posterior fossa;
Bacterial meningitis;
Infant, newborn
- From:
Chinese Journal of Applied Clinical Pediatrics
2021;36(18):1428-1430
- CountryChina
- Language:Chinese
-
Abstract:
The clinical data of a case of neonatal bacterial meningitis complicated with posterior fossa subdural empyema in the West China Second University Hospital in December 2019 were retrospectively analyzed.The 3-day-old male newborn was admitted for jaundice with decreased intake for 1 day.Examinations on admission showed increased C-reactive protein.The count of karyocytes in cerebrospinal fluid (CSF) significantly increased, which were mainly neutrophils, and pyocytes could be found.The protein content in CSF increased, while that of glucose decreased.Both CSF culture and blood culture detected the presence of Escherichia coli.Enhanced magnetic resonance imaging (MRI) of the head indicated large abnormal signals in bilateral occipital extra-cerebellar spaces.T1-weighted images presented mixed low and high signals, and T2-weighted images presented high signals, and marginal enhancement was observed after enhancement.After 6 weeks of antibiotic treatment using Meropenem combined with Ceftazidime, the CSF index of the newborn patient returned to normal, and the subdural empyema of the posterior fossae subsided.Bacterial meningitis complicated with subdural empyema of posterior fossa is a rare and critical disease of the central nervous system.It is easily misdiagnosed due to the atypical clinical manifestations and early imaging features.The disease requires an adequate course of anti-infective treatment.Surgical removal of the empyema should be performed if the anti-infective treatment is unresponsive.
