Interpretation of European Academy of Allergy and Clinical Immunology Biologicals Guidelines-Recommendations for severe asthma

VernacularTitle:欧洲过敏和临床免疫学会重症哮喘生物制剂治疗指南解读
Author: Peng HAN ¹ ; Kunling SHEN
Author Information

1. 国家儿童医学中心，首都医科大学附属北京儿童医院呼吸科，国家呼吸系统疾病临床医学研究中心，北京　100045
Keywords: Biological; Guideline interpretation; Severe asthma; Child
From: Chinese Journal of Applied Clinical Pediatrics 2021;36(12):891-896
CountryChina
Language:Chinese
Abstract: Severe asthma imposes a significant burden on patients, families, and healthcare systems.Management is difficult, due to disease heterogeneity, co-morbidities, complexity in care pathways and differences between national or regional healthcare systems.Better understanding of the mechanisms has enabled a stratified approach to the management of severe asthma, supporting the use of targeted treatments with biologicals.However, there are still many issues that require further clarification.These include selection of a certain biological, the definition of response, strategies to enhance the responder rate, the duration of treatment and its regimen.