Clinical efficiency evaluation and prognostic factors of aspiration guided by neuronavigation to treat pediatric brain abscess
10.3760/cma.j.cn101070-20200227-00282
- VernacularTitle:神经导航辅助下穿刺抽吸治疗儿童脑脓肿的疗效及预后因素分析
- Author:
Meng WANG
1
;
Yi ZHAO
;
Peichao ZHAO
;
Peng ZHANG
;
Yuanyuan PAN
;
Tianhao LI
;
Xueyou LIU
;
Zeming WANG
;
Chengming QIU
;
Rende ZHANG
;
Hongwei SUN
Author Information
1. 郑州大学第一附属医院神经外科 450052
- Keywords:
Brain abscess;
Neuronavigation;
Aspiration;
Child;
Prognosis factor
- From:
Chinese Journal of Applied Clinical Pediatrics
2021;36(11):865-869
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical efficiency evaluation and prognostic factors of aspiration guided by neuronavigation in the treatment of pediatric brain abscess (PBA).Methods:A total of 47 patients with PBA were treated with aspiration guided by neuronavigation between January 2013 and January 2019 at the First Affiliated Hospital of Zhengzhou University.All clinical data were retrospectively analyzed.According to Glasgow Outcome Scale on discharge, all children were divided into 2 groups, namely good prognosis group and poor prognosis group.Prognostic factors were analyzed by using univariate analysis and binary Logistic regression multivariate analysis. Results:Among the 47 children, 38 children (80.9%) were assigned to the good prognosis group, and 9 children (19.1%) were assigned to the poor prognosis group.Univariate analysis proved that abscess volume>4 cm( χ2=5.650, P=0.017), multiple or multilocular abscess ( χ2=3.258, P=0.027), and abscess located in functional areas ( χ2=6.187, P=0.013) were correlated with poor prognosis.Multivariate analysis revealed that abscess volume>4 cm( OR=5.913, 95% CI: 2.241-25.917, P=0.023) and abscess located in functional areas ( OR=10.519, 95% CI: 3.918-62.513, P<0.001) were independent risk factors for poor prognosis. Conclusion:The treatment of PBA with aspiration guided by neuronavigation is safe, effective and minimal invasive, and the clinical efficiency is satisfactory.Abscess volume>4 cm and abscess located in deepbrain/functional areas are independent risk factors for poor prognosis.
