Prevention and treatment of calcium and/or vitamin D insufficiency associated parathyroid hyperfunction and hyperparathyroidism
10.3760/cma.j.cn.115807-20210620-00184
- VernacularTitle:钙剂摄入不足和（或）维生素D缺乏/不足相关甲状旁腺功能增强和亢进症的转归与防治
- Author:
Lingquan KONG
1
;
Juan WU
;
Ying LI
;
Shu LI
;
Zhaoxing LI
;
Xinyu LIANG
;
Shen TIAN
;
Hao LI
;
Hongyuan LI
;
Kainan WU
Author Information
1. 重庆医科大学附属第一医院内分泌乳腺外科 400016
- Keywords:
Hyperparathyroidism;
Calcium and/or vitamin D insufficiency;
Parathyroid hyperfunction;
Pre-hyperparathyroidism;
Calcium and/or vitamin D insufficiency as
- From:
Chinese Journal of Endocrine Surgery
2021;15(4):337-341
- CountryChina
- Language:Chinese
-
Abstract:
Hyperparathyroidism is a common endocrine disease that seriously affects human health, depending on its etiology, which can be divided into three types: primary, secondary and tertiary. In clinical practice, we found that some primary hyperparathyroidism may be secondary or tertiary hyperparathyroidism caused by insufficient calcium intake and/or vitamin D deficiency/insufficiency, and become a common type of hyperparathyroidism. The daily calcium intake of Chinese people is generally insufficient. Vitamin D can promote the absorption of calcium, but vitamin D deficiency/insufficiency is also a worldwide public health problem. Long-term hypocalcemia will stimulate parathyroid hyperplasia and secrete excessive parathyroid hormone, resulting in parathyroid hyperfunction (pre-hyperparathyroidism) and then secondary hyperparathyroidism, both of which may damage bone and release calcium into blood, leading to diseases of multiple organs and tissues. The detection of bone metabolism indexes such as calcium, magnesium, phosphorus, parathyroid hormone and vitamin D may be helpful for the early diagnosis of pre-hyperparathyroidism and hyperparathyroidism. Supplementation of calcium and vitamin D in early stage can control the development of the disease and change "unpreventable and uncontrollable" into "preventable and controllable" . The health screening of bone metabolism indexes and parathyroid ultrasonography should be advocated, and the prevention and treatment of calcium and/or vitamin D insufficiency associated parathyroid hyperfunction and hyperparathyroidism should be strengthened, so as to greatly improve the bone health, urinary calculus, metastatic vascular calcification and systemic abnormal calcium migration and precipitation in the population.
