Clinical study on non-fasting blood lipids in patients with type 2 diabetes
10.3760/cma.j.cn.115807-20190609-00109
- VernacularTitle:2型糖尿病患者非空腹血脂检测的临床研究
- Author:
Dawei WU
1
;
Shuangqing LIU
;
Li NING
Author Information
1. 天津医科大学第二医院检验科 300211
- Keywords:
Diabetes;
Blood lipid;
Cardiovascular disease;
Non-fasting blood lipid
- From:
Chinese Journal of Endocrine Surgery
2021;15(3):239-242
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the feasibility of non-fasting blood lipid detection in patients with type 2 diabetes mellitus (T2DM) .Methods:A total of 426 diabetic patients hospitalized in the Second Hospital of Tianjin Medical University from Oct. 2018 to Apr. 2019 were selected to collect blood samples from the fasting and non-fasting state of the patients respectively. The levels of plasma three acylglycerol (TG) , total cholesterol (TC) , high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) were measured at the same time, and self-control method was used. The results of two tests were compared with the wilcoxon signed-rank test.Results:Compared with the fasting results, non-fasting TG increased by 0.25 mmol/L (11.2%) , with statistical significance ( P<0.05) ; TC increased by 0.17 mmol/L (4.5%) , HDL-C increased by 0.08 mmol/L (5.7%) , and LDL-C decreased by 0.05 mmol/L (5.9%) , without significant differenc ( P>0.05) . Conclusion:Except for TG, non-fasting TC, HDL-C, LDL-C has little change compared with those in fasting state, which can replace fasting blood lipid detection as a method for detecting blood lipid profile in patients with T2DM.
