A Case of IgG4-Related Sclerosing Disease Involving the Eyelid in an Idiopathic Sclerosing Myositis Patient.
10.3341/jkos.2013.54.1.160
- Author:
Je Hwan YOON
1
;
Jee Woong JUNG
;
Mi Jung CHI
Author Information
1. Department of Ophthalmology, Gachon University Gil Medical Center, Incheon, Korea. cmj@gilhospital.com
- Publication Type:Case Report
- Keywords:
Eyelid;
Idiopathic sclerosing myositis;
IgG4-related sclerosing disease;
Lacrimal gland
- MeSH:
Biopsy;
Dacryocystitis;
Diagnosis, Differential;
Exophthalmos;
Eye Movements;
Eyelids*;
Female;
Humans;
Lacrimal Apparatus;
Magnetic Resonance Imaging;
Middle Aged;
Muscles;
Myositis*;
Orbit;
Steroids
- From:Journal of the Korean Ophthalmological Society
2013;54(1):160-164
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report a case of IgG4-related sclerosing disease involving the eyelid in an idiopathic sclerosing myositis patient. CASE SUMMARY: A 51-year-old woman presented with swelling, redness, and tenderness of the left lower eyelid of 1 month duration had taken an immunosuppressant for idiopathic sclerosing myositis. Eye movements showed limitation all directions but there was no exophthalmos. A palpable mass was noted in the left lower eyelid. The left extraocular muscles were hypertrophied but the lacrimal gland was normal on orbital magnetic resonance imaging. IgG4-related sclerosing disease was confirmed by immunostained biopsy from the left lower eyelid, showing infiltration of IgG4-positive lymphoplasmacytic cells. The patient was given oral steroids and an immunosuppressant and the symptoms did not recur for at least 7 months. CONCLUSIONS: IgG4-related sclerosing disease involving ocular adnexa usually consists of bilateral lacrimal gland involvement. Additionally, the orbital soft tissue involvement without dacryoadenitis is rare. The authors of the present study report a case of IgG4-related sclerosing disease involving the left lower eyelid in an idiopathic sclerosing myositis patient and should be considered in the differential diagnosis of eyelid masses.
