Retrospective analysis of clinical characteristics of 78 patients receiving extracorporeal cardiopulmonary resuscitation
10.3760/cma.j.issn.1671-0282.2021.10.005
- VernacularTitle:78例体外心肺复苏患者的临床特点回顾性分析
- Author:
Wei LI
1
;
Jinsong ZHANG
;
Xufeng CHEN
;
Yong MEI
;
Jinru LV
;
Deliang HU
;
Feng SUN
;
Gang ZHANG
;
Huazhong ZHANG
;
Xihua HUANG
;
Hui ZHANG
;
Weiwei WANG
Author Information
1. 南京医科大学第一附属医院（江苏省人民医院）急诊医学科 210029
- Keywords:
Extracorporeal cardiopulmonary resuscitation;
Cardiac arrest;
SAVE(Survival After Veno-arterial ECMO)core
- From:
Chinese Journal of Emergency Medicine
2021;30(10):1187-1191
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize the clinical characteristics and influencing factors on clinical outcome of patients receiving extracorporeal cardiopulmonary resuscitation (ECPR).Methods:A total of 78 patients receiving ECPR admitted to the Department of Emergency Medicine of the First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People’s Hospital) from March 2015 to December 2020 were retrospectively enrolled. Patients were divided into the survival group and death group according to clinical outcome. Their baseline data, CPR associated parameters, and pre-ECPR laboratory tests were compared between the two groups.Results:Of the 78 included patients, 51 patients were male and 27 female. Twenty-three patients finally survived, including 10 males and 13 females. There were no significant differences in age, body mass index and underlying diseases (hypertension, diabetes and coronary heart disease) between the two groups (all P > 0.05). The proportion of male patients in the survival group was lower than that in the death group ( P=0.017). Meanwhile Survival After Veno-Arterial ECMO (SAVE) score was significantly higher in the survival group than that in the death group[ (-1.57±4.15) vs. (-9.36±5.36), P<0.001]. The proportion of by-stander CPR in the survival group was higher than that in the death group ( P=0.014). The pre-ECPR serum AST, ALT, and Cr levels in the survival group were significantly lower than those in the death group (all P<0.05). Logistic regression analysis showed that by-stander CPR ( OR=0.114, 95% CI: 0.015~0.867, P=0.036) and SAVE score ( OR=0.625, 95% CI: 0.479~0.815, P=0.001) were independent risk factors predicting ICU death in patients receiving ECPR. Conclusions:ECPR is an efficient tool to improve clinical outcomes of patients with cardiac arrest. By-stander CPR and SAVE score are independent risk factors predicting ICU death in patients receiving ECPR.
