Platelet transfusion practice and related outcomes in patients with veno-arterial extracorporeal membrane oxygenation: a three-year retrospective study
10.3760/cma.j.issn.1671-0282.2021.10.003
- VernacularTitle:血小板输注量对动脉-静脉体外膜肺氧合患者预后的影响：一项连续三年的回顾性研究
- Author:
Yi ZHU
1
;
Xufeng CHEN
;
Jinsong ZHANG
;
Yong MEI
;
Jinru LV
;
Gang ZHANG
;
Deliang HU
;
Wei LI
;
Huazhong ZHANG
;
Feng SUN
;
Juan WU
;
Yongxia GAO
;
Xihua HUANG
;
Hui ZHANG
Author Information
1. 南京医科大学第一附属医院急诊医学中心 210029
- Keywords:
ECMO;
Platelets;
Myocarditis;
Prognosis;
Transfusion.
- From:
Chinese Journal of Emergency Medicine
2021;30(10):1177-1181
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the application of blood products in patients with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and evaluate its effect on the prognosis.Methods:A total of 83 adult patients treated with VA-ECMO in the Emergency Department of the First Affiliated Hospital of Nanjing Medical University from January 2017 to January 2020 were grouped by survival to explore the risk factors of 28-day mortality using binary logistic regression, and the threshold was calculated by ROC curve.Results:Platelet transfusion ( OR=2.506, 95% CI: 1.142-5.499) and non-myocarditis disease ( OR=6.881, 95% CI: 1.615-29.316) were the risk factors of 28-day mortality in adult VA-ECMO patients. The threshold of platelet transfusion was 0.427 mL/(kg·d) (sensitivity 78.4%, specificity 69.6% , AUC 0.735). Conclusions:The increased platelet transfusion is related to the poor prognosis of adult patients with VA-ECMO. Refractory myocarditis patients are better treated with VA-ECMO.
