Analysis to early warning of blood growth differentiation factor-15 in high intensity training
10.3760/cma.j.issn.1671-0282.2021.06.008
- VernacularTitle:血生长分化因子-15在高强度训练中预警分析
- Author:
Yunjing SHENG
1
;
Qinrui XING
;
Tingli WANG
;
Shangqing CHANG
;
Haiyan ZHU
Author Information
1. 南方医科大学第二临床医学院，广东省广州市，510000，中国
- Keywords:
Stress response;
GDF15;
High-intensity training;
S-CRP;
CRP;
IL-6;
PCT;
Early warning
- From:
Chinese Journal of Emergency Medicine
2021;30(6):685-688
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the early warning of blood growth differentiation factor-15 (GDF15) as a new stress indicator.Methods:A total of 53 armed police soldiers selected to participate in high-intensity training, measuring the soldiers' serum GDF15, high-sensitivity C-reactive protein (S-CRP), and C-reactive protein (CRP) before and after the high-intensity training , Interleukin-6 (IL-6), Procalcitonin (PCT) levels, compare the coefficient of variation of each index; use SPSS 24 software for statistical analysis, measurement data are expressed as mean ± standard deviation (Mean±SD), The comparison of measurement data adopts group t test. Results:The GDF15 level of fighters after high-intensity training was (176.28±97.45) pg/mL, which was higher than (120.35±69.87) pg/mL before high-intensity training. The difference was very significant ( P <0.001). After high-intensity training, IL-6 and CRP levels were lower than before high-intensity training, the difference was statistically significant ( P<0.05); there was no statistically significant difference in S-CRP and PCT before and after high-intensity training ( P>0.05). The coefficient of variation of GDF15 index is smaller than S-CRP, CRP, IL-6, PCT. Conclusion:Blood growth differentiation factor-15 (GDF15) is of great significance in warning the stress state after high-intensity training. It has higher sensitivity than other conventional stress indicators like S-CRP, CRP, IL-6 and PCT.
