Advances in neoadjuvant therapy of esophageal cancer involved in organ preservation
10.3760/cma.j.cn371439-20201111-00133
- VernacularTitle:食管癌新辅助治疗参与保存器官的研究进展
- Author:
Chen DU
1
;
Siyu SU
;
Lige WANG
;
Guiping YU
Author Information
1. 西安市第九医院肿瘤分院放疗科 710000
- Keywords:
Esophageal neoplasms;
Neoadjuvant therapy;
Organ preservation;
Comprehensive treatment
- From:
Journal of International Oncology
2021;48(11):673-677
- CountryChina
- Language:Chinese
-
Abstract:
Esophageal squamous cell carcinoma is one of the most common cancer in China, and locally advanced stage remains a heterogeneous and complex disease. Its treatments are constantly evolving. To date, radiochemotherapy and surgery are involved in the comprehensive treatment of this disease. However, because of the specifical anatomical location of esophagus, its physiological function will be impaired after surgical resection. If similar survival is obtained in esophageal cancer, an organ preserving strategy without surgery is of great significance for improving the quality of life. As a non-invasive tumor treatment method, neoadjuvant therapy plays an important role in the comprehensive treatment of preserving the esophagus. Recently, there are studies investigating the role of organ preserving strategy in the comprehensive treatment of esophageal cancer with neoadjuvant therapy, and the recognition of these advances will provide reference value for the comprehensive treatment of esophageal cancer.