Research progress of arsenic trioxide in anti-liver cancer mechanism and treatment of hepatocellular carcinoma

VernacularTitle:三氧化二砷抗肝癌机制及其在肝癌治疗中的研究
Author: Jiahang DU ¹ ; Dong CHEN ; Yaoting CHEN
Author Information

1. 中山大学孙逸仙纪念医院介入放射科，广州　510120
Keywords: Liver neoplasms; Therapeutic uses; Arsenic trioxide
From: Journal of International Oncology 2021;48(9):572-574
CountryChina
Language:Chinese
Abstract: Arsenic trioxide (ATO) is involved in a variety of biological processes of hepatocellular carcinoma (HCC) cells, including apoptosis induction, proliferation inhibition, invasion and metastasis inhibition, and tumor stem cell inhibition. ATO has a variety of therapeutic approaches in the treatment of HCC, mainly including single drug therapy, combined local therapy, combined systemic therapy, and so on. Further research on the anti-cancer mechanism and clinical application of ATO is expected to provide new ideas for the treatment of liver cancer.