Clinical significance of exosomal-circRNA in tumor diagnosis and treatment
10.3760/cma.j.cn371439-20210206-00106
- VernacularTitle:外泌体-环状RNA在肿瘤诊治中的临床意义
- Author:
Wanchen ZHANG
1
;
Jiajie XU
;
Lizhuo ZHANG
;
Minghua GE
Author Information
1. 浙江中医药大学第二临床医学院,杭州 310053
- Keywords:
Exosomes;
Neoplasms;
Circular RNA
- From:
Journal of International Oncology
2021;48(9):549-552
- CountryChina
- Language:Chinese
-
Abstract:
There are abundant and stable circular RNAs in tumor-derived exosomes, which play an important role in the occurrences and developments of tumors. Exosome-circRNAs can be used as the marker of tumors diagnosis and prognosis, and have different roles in regulating tumors immune responses, regulating tumors progressions and mediating tumors drug resistances in different tumors. Exploring and applying the potential value of exosome-circRNAs will provide a new choice for the diagnosis and treatment of tumors.