Mechanism study of CeRNA regulatory network mediating malignant tumor phenotype

VernacularTitle:CeRNA网络介导恶性肿瘤表型调控的机制研究
Author: Jing ZHANG ¹ ; Shouguo HUANG ; Ying XIA
Author Information

1. 中南大学湘雅医学院附属海口医院妇产科　570208
Keywords: Gene expression regulation, neoplastic; RNA, long noncoding; Phenotype; CeRNA
From: Journal of International Oncology 2021;48(9):544-548
CountryChina
Language:Chinese
Abstract: Competing endogenous RNAs (CeRNAs) are crisscrossing regulatory networks. CeRNAs networks can mediate malignant tumor cell phenotypes, including proliferation and inhibition, autophagy, infinite growth, induction of angiogenesis and angiogenic mimicosis, immune escape, etc.. It is expected to provide new diagnostic markers and therapeutic targets for malignant tumors to master the regulation and function of CeRNAs mediated phenotype in malignant tumors.