Diagnosis, treatment and prognosis of human major exocrine ductal carcinoma
10.3760/cma.j.cn371439-20210602-00087
- VernacularTitle:人体主要外分泌腺导管癌的诊疗与预后
- Author:
Pingchuan MA
1
;
Chunjie LI
;
Longjiang LI
Author Information
1. 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心 四川大学华西口腔医院头颈肿瘤外科，成都 610041
- Keywords:
Ductal carcinoma;
Diagnose;
Molecular targeted therapy;
Prognosis
- From:
Journal of International Oncology
2021;48(8):449-455
- CountryChina
- Language:Chinese
-
Abstract:
Exocrine ductal carcinoma is an important part of malignant tumors of exocrine glands, including invasive breast ductal carcinoma, salivary duct carcinoma, pancreatic ductal adenocarcinoma and cholangiocarcinoma. Most of these diseases are aggressive, highly malignant and endanger human health. Early detection and diagnosis are the key to a good prognosis for exocrine ductal carcinoma. Different exocrine ductal carcinomas also have certain connections, and their molecular biological characteristics, pathological characteristics and molecular mechanisms have similarities. Surgical resection combined with adjuvant radiotherapy and chemotherapy is currently a common treatment method for exocrine ductal carcinoma. At the same time, its related targeted therapy and immunotherapy sites can also learn from each other. Human epidermal growth factor receptor-2 (HER-2) and the family markers have become breast ductal carcinoma and salivary duct carcinoma targeted therapy sites, and immunotherapy at programmed death ligand 1 (PD-L1) sites has also been involved in many studies, but there is no clear conclusion yet.
