Research progress of fibrinogen, NLR and F-NLR grading in gastric cancer
10.3760/cma.j.cn371439-20201230-00083
- VernacularTitle:纤维蛋白原、NLR及F-NLR评分在胃癌中的研究进展
- Author:
Yinjing YANG
1
;
Guixiang LI
;
Min TANG
Author Information
1. 兰州大学第二医院肿瘤中心伽马刀治疗科 730030
- Keywords:
Stomach neoplasms;
Fibrinogen;
Prognosis;
Neutrophil to lymphocyte ratio
- From:
Journal of International Oncology
2021;48(7):433-435
- CountryChina
- Language:Chinese
-
Abstract:
Multiple markers that related to gastric cancer has been widely used in clinical, to predict its occurrence, development and prognosis. Serum level of fibrinogen (FIB) and neutrophil to lymphocytes ratio (NLR) respectively as representative indicators of coagulation system and inflammation, can predict the prognosis of patients with gastric cancer and survival time. The rise of fibrinogen is associated with enhanced capacity of the gastric tumor cells proliferation, invasion and migration. High NLR is associated with significantly induced survival of patients with gastric cancer. The combination of fibrinogen and NLR (F-NLR) combines the advantages of each individual indicator in predicting the occurrence, development and prognosis of cancer. It has shown a great prognostic potential in gastric cancer, and can be widely applied in prospect.
