Research on the correlation between driver genes of lung adenocarcinoma and venous thromboembolism
10.3760/cma.j.cn371439-20201119-00071
- VernacularTitle:肺腺癌驱动基因与静脉血栓栓塞症相关性研究
- Author:
Tiantian LI
1
;
Licheng SHI
;
Hui KONG
;
Xu QI
Author Information
1. 南京医科大学第一附属医院呼吸与危重症医学科 210029
- Keywords:
Lung neoplasms;
Adenocarcinoma;
Venous thromboembolism;
Driver gene
- From:
Journal of International Oncology
2021;48(6):370-373
- CountryChina
- Language:Chinese
-
Abstract:
Venous thromboembolism (VTE) is one of the common complications of lung adenocarci-noma. The state of the driver genes of lung adenocarcinoma is related to the risk of VTE. The common driver genes include epidermal growth factor receptor, anaplastic lymphoma kinase, c-ros oncogene 1 receptor kinase and Kirsten rat sarcoma viral oncogene, etc.. Based on the study of the correlation between lung adenocarci-noma driver genes and VTE, it is of great significance for the early clinical prevention of VTE in patients with lung adenocarcinoma to screen out patients with high risk of VTE according to the state of the driver genes and finally evaluate the risk of VTE in patients with lung adenocarcinoma by combining conventional risk factors with the driver genes.