Role of new immune checkpoints in tumor treatment
10.3760/cma.j.cn371439-20201119-00067
- VernacularTitle:新型免疫检查点在肿瘤治疗中的作用
- Author:
Yuanling WU
1
;
Weizhen SHOU
Author Information
1. 上海中医药大学附属龙华医院胸外科 200032
- Keywords:
Neoplasms;
Therapy;
Immune checkpoint
- From:
Journal of International Oncology
2021;48(6):354-357
- CountryChina
- Language:Chinese
-
Abstract:
New immune checkpoint targets such as lymphocyte activation gene-3, T-cell immunoglobulin mucin-3, T cell immunoglobulin and ITIM domain, V-domain immunoglobulin suppressor of T cell activation, B7 Homolog 3, B and T lymphocyte attenuator play an important role in tumor treatment. Blocking them can delay tumor growth, enhance the anti-tumor effect of immune cells, and improve the survival rate of the host. Although these new immune checkpoints are in the early stages of research, with the continuous development of science and technology, they will play an increasingly important role in tumor immunotherapy.