Regulation of IL-35, IL-39 and IL-27 in tumor microenvironment
10.3760/cma.j.cn371439-20200722-00042
- VernacularTitle:IL-35、IL-39、IL-27在肿瘤微环境中的调节作用
- Author:
Saisai LIU
1
;
Dongya YUAN
Author Information
1. 西藏民族大学西藏自治区高原相关疾病分子遗传机制与干预研究重点实验室,咸阳 712082
- Keywords:
Tumor microenvironment;
Immunity;
Cytokines
- From:
Journal of International Oncology
2021;48(4):212-215
- CountryChina
- Language:Chinese
-
Abstract:
The interleukin family can directly or indirectly stimulates the proliferation, survival and diffusion of tumor cells, and further shapes the tumor microenvironment, thus affecting the tumor growth and transformation to a certain extent. Studies show that the new numbers of IL-12 family, IL-35, IL-39 and IL-27, play the relevant specific immune functions in a variety of tumors, which may be important target molecules for tumors research.