Research progress on the expression of CPNE in malignant tumor and its effect on invasion and metastasis

VernacularTitle:CPNE在恶性肿瘤中的表达及其对侵袭转移影响的研究进展
Author: Bangguo KOU ¹ ; Yongjie JIANG ; Pan BIAN ; Bingtai LI ; Lanning YIN
Author Information

1. 兰州大学第二医院普外六科　730030
Keywords: Neoplasm invasiveness; Neoplasm metastasis; Review; CPNE; Malignant tumor
From: International Journal of Surgery 2021;48(11):788-792
CountryChina
Language:Chinese
Abstract: Malignant tumor has become one of the main reasons threatening human health. Invasion and metastasis are the important biological characteristics of malignant tumor and the main cause of death of malignant tumor patients. CPNE is highly expressed in malignant tumors, and its family may interact with proteins and MicroRNA to participate in MAPK, PI3K/AKT and other signal pathways to mediate tumor cell proliferation, invasion and metastasis. This article reviews the expression of CPNE in malignant tumors and its effect on invasion and metastasis.