Research progress of the risk of rupture of unruptured intracranial aneurysm
10.3760/cma.j.cn115396-20210904-00346
- VernacularTitle:颅内未破裂动脉瘤破裂风险因素研究进展
- Author:
Yuhao DING
1
;
Jianren WANG
;
Tao XIE
;
Xi′an FU
Author Information
1. 南京医科大学附属苏州医院神经外科 215008
- Keywords:
Intracranial aneurysms;
Pathogenesis;
Morphology;
Hemodynamic;
Risk of rupture
- From:
International Journal of Surgery
2021;48(10):700-705
- CountryChina
- Language:Chinese
-
Abstract:
Intracranial aneurysms will lead to subarachnoid hemorrhage, which has a high mortality and morbidity risk. Screening high-risk aneurysms for preventive intervention has a positive effect, considering the widespread presence of unruptured aneurysms in the general population, this article reviews the risk factors of aneurysm rupture from the aspects of epidemiology, pathology, morphology and hemodynamics. In terms of epidemiology, smoking history, hypertension, age, gender and family inheritance are all closely related to the risk of aneurysm rupture. In terms of pathology, inflammation on the wall of intracranial aneurysm may be related to the risk of aneurysm rupture. In imaging, the size of intracranial aneurysms, location, the characteristics of the artery wall and some morphological and hemodynamic parameters can be used as evaluation index of fracture risk factors, at the same time the growth of intracranial aneurysm is one of the high risk indicators, the indicators for us in the future to establish intracranial unruptured aneurysms rupture risk factors evaluation model is of great significance.