Negative effect of prolonged postoperative ileus on postoperative recovery in patients underwent open alimentary tract surgery
10.3760/cma.j.issn115396-20210506-00168
- VernacularTitle:腹部手术延迟性术后肠麻痹对术后康复的不良影响
- Author:
Jianning SONG
1
;
Fandi BU
;
Lan JIN
;
Jun LI
;
Yun YANG
;
Guocong WU
;
Hongwei YAO
;
Jin WANG
;
Zhongtao ZHANG
;
Yingchi YANG
Author Information
1. 首都医科大学附属北京友谊医院普外科，国家消化系统疾病中心普外分中心 100050
- Keywords:
Abdomen;
Surgical procedures, operative;
Length of stay;
Prolonged postoperative ileus;
Healthcare cost
- From:
International Journal of Surgery
2021;48(8):553-559
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the negative effect of prolonged postoperative ileus on postoperative recovery in patients underwent open alimentary tract surgery.Methods:This study was a retrospective cohort study. The subjects of the study were patients who underwent open gastrointestinal surgery at the General Surgery Department of Beijing Friendship Hospital, Capital Medical University from October 2016 to November 2018. According to the PPOI diagnostic criteria proposed by the University of Auckland, the included patients were classified as PPOI Group ( n=14) and non-PPOI group ( n=112). The postoperative complications, postoperative hospital stay and medical expenses during hospitalization were selected as the study endpoint indicators. T-test or Fisher′s exact test were performed to compare the differences between the two groups, and linear regression analysis was used to explore the independent effects of PPOI on hospital stay and medical expenses. Results:The incidence of PPOI in this study cohort was 11.1%. The total postoperative complications occurred more frequent in PPOI group (64.29% vs 38.39%, P=0.08). The average postoperative hospital stay of patients in the PPOI group was longer than that in non-PPOI group [(21.21±14.83) d vs (13.98±14.21) d, P=0.070]. Adjusting for various possible confounding factors, the PPOI regression coefficient beta (95% CI) that affects the length of hospital stay was [-0.43 (-7.16, 6.3), P=0.90]. The average medical cost of patients in the PPOI group was more than that in non-PPOI group [(104 389.64±52 427.66)元比(79 111.41±50 832.29)元, P=0.070]. Adjusting for various possible confounding factors, the PPOI regression coefficient beta (95% CI) that affects medical expenditure was [-134.12 (-21656.85, 21388.62), P=0.99]. Conclusions:Prolonged postoperative ileus leads to delayed postoperative recovery, which is related to increased postoperative complications, hospital stay duration and medical cost. But it needs further confirmation from large sample data.
