Research progress on time and dose selection of indocyanine green in laparoscopic cholecystectomy
10.3760/cma.j.cn115396-20210527-00194
- VernacularTitle:吲哚菁绿在腹腔镜胆囊切除术中时间及剂量选择的研究进展
- Author:
Qingsheng FU
1
;
Tao LI
;
Xudong ZHANG
;
Chunfu ZHU
;
Xihu QIN
;
Baoqiang WU
Author Information
1. 蚌埠医学院研究生学院 233030
- Keywords:
Cholecystectomy, laparoscopic;
Time;
Injections;
Indocyanine green;
Dose;
Biliary duct injury
- From:
International Journal of Surgery
2021;48(7):472-477,F3
- CountryChina
- Language:Chinese
-
Abstract:
In the era of precision medicine, compared with open surgery, laparoscopic cholecystectomy has the advantages of less trauma, less postoperative complications and shorter hospital stay, but it cannot escape the risk of bile duct injury, and bile duct injury can occur at any time for various reasons, and its unpredictability greatly increases the difficulty of surgery. Although traditional cholangiography can avoid bile duct injury, it has not been widely used due to its limitations such as time consuming, high cost, high radiation and so on. Early indocyanine green has been widely used in lymph node examination, angiography, tumor localization and treatment due to its characteristics. Now, indocyane green fluorescence imaging technology has been gradually applied in LC, which can dynamically reflect the intraoperative situation and realize real-time surgical navigation, so it has achieved ideal effects in the identification of duct structure and prevention of bile duct injury. Indocyanine green injection preoperatively or intraoperatively through the gallbladder to develop extrahepatic bile ducts significantly improves the safety rate of surgery, but there is no unified standard for the use time and dosage of inddocyanine green. In this paper, the time and dose selection and clinical value of indocyanine green were reviewed based on the current research status and the author's experience.