T Helper cell 17/regulatory T cell balance and ischemic stroke
10.3760/cma.j.issn.1673-4165.2021.10.011
- VernacularTitle:辅助性T细胞17/调节性T细胞平衡与缺血性卒中
- Author:
Mengxin CAO
1
;
Zijun WEI
;
Yunyun ZHANG
Author Information
1. 上海中医药大学附属岳阳中西医结合医院神经内科 200437
- Keywords:
Stroke;
Brain ischemia;
Th17 cells;
T-Lymphocytes, regulatory
- From:
International Journal of Cerebrovascular Diseases
2021;29(10):781-784
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory immune response runs through the course of ischemic stroke. Different subgroups of CD4 + T cells play a complex and important role in the course of ischemic stroke. Among them, the balance of pro-inflammatory effect of T helper cell 17 (Th17) and anti-inflammatory effect of regulatory T cells (Treg) is closely associated with the outcome of stroke. This article reviews the role of Th17/Treg balance in ischemic stroke, in order to deepen the understanding of the mechanism of immune inflammation after ischemic stroke and explore possible therapeutic targets in the course of ischemic stroke.
