Mechanism of period gene regulating renin-angiotensin-aldosterone system in rhythm of blood pressure
10.3760/cma.j.issn.1673-4165.2021.08.013
- VernacularTitle:Period基因调控肾素-血管紧张素-醛固酮系统在血压节律中的作用机制
- Author:
Siyuan CHEN
1
;
Jing JIN
;
Dong ZHANG
;
Jian GE
;
Yumeng LIU
;
Haiyuan SHI
;
Mingli HE
Author Information
1. 徐州医科大学 221004
- Keywords:
Blood pressure;
Period circadian proteins;
CLOCK proteins;
Circadian clocks;
Renin-angiotensin system;
Aldosterone;
Gene Expression regulation
- From:
International Journal of Cerebrovascular Diseases
2021;29(8):630-635
- CountryChina
- Language:Chinese
-
Abstract:
Rhythm of blood pressure refers to the circadian variation of blood pressure, which is regulated by clock genes. However, the rhythm disorder of blood pressure increases the risk of stroke. Taking the process of blood pressure regulation as a clue and focusing on the clock gene pathway, this article explores the possible mechanism of period gene regulating renin-angiotensin-aldosterone system in rhythm of blood pressure, so as to provide reference for the in-depth study of the relevant mechanism of rhythm disorder of blood pressure and search for a new target for the primary prevention of cerebrovascular diseases.
