Clinical Significance of Endometrial Thickness and Pattern in Ovum Donation and Cryopreserved - Thawed Embryo Transfer Program.
- Author:
Shin Yong MOON
;
Young Min CHOI
;
Seok Hyun KIM
;
Chang Suk SUH
;
Jin Yong LEE
;
Jung Gu KIM
;
Byung Chul JEE
;
Seo Yeong PARK
- Publication Type:Original Article
- Keywords:
Endometrial thickness;
Endometrial pattern;
Ovum donation;
Cryopreserved-thawed embryo transfer
- MeSH:
Embryo Transfer*;
Embryonic Structures*;
Estrogens;
Fertilization;
Oocyte Donation*;
Ovum*;
Progesterone;
Prospective Studies
- From:Korean Journal of Obstetrics and Gynecology
1999;42(2):287-295
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To investigate the clinical significance of endometrial thickness and pattan as a predictor of successful implantation of embryos in ovum donation and cryopreserved-thawed embryo transfer program. METHODS: From January, 1996 to March, 1998, 31 cycles of ovum donation and 31 cycles of cryopreserved-thawed embryo transfer were enrolled in this prospective study. Endometrial thickness was measured three times: prior to progesterone administration (P), 1 day and 3 days after P. In cryopreserved-thawed embryo transfer cycles, the measurement at 1 day after P was omitted. Endometrial pattern was observed prior to progesterone, and was considered meaningful when a multi-layered triple-line was seen with prominent outer and central hyperchogenic lines and inner hypoechogenic regions. RESULTS: There were no differences in embryo quality, dose or duration of estrogen, and endometrial thickness or pattern between conception and non-conception cycles in both ovum donation and cryapreserved-thawed embryo transfer pmgram. In ovum donation cycles, no cortelation was observed between estrogen dose and endometrial thickness or pattern. In cryopreserved-thawed embryo transfer cycles, total estrogen dose and endometral thickness at 3 days after P has a inverse correlation, and estrogen dose over 4.3 mg per day can predict expression of a multi-layered triple-line pattern, CONCLUSION: Endometrial thickness or pattern. cannot predict a successful implantaion of embryos in both ovum donation and cryopreserved-thawed embryo transfer cycles.
